by MH Team | Oct 9, 2023 | White Blood Cells
Key Takeaways Chronic myeloid leukemia is a slow-growing blood cancer caused by the BCR-ABL1 fusion gene on the Philadelphia chromosome, formed by a swap between chromosomes 9 and 22. Pathogenesis ▾: Signs and symptoms ▾: Most patients are diagnosed in...
by MH Team | Oct 9, 2023 | White Blood Cells
Key Takeaways Chronic lymphocytic leukemia also known as CLL is a slow progressing cancer due to overgrowth and accumulation of small incompetent mature-looking B-lymphocytes in the blood, bone marrow and lymphoid tissues. Small lymphocytic leukemia is a different...
by MH Team | Oct 9, 2023 | White Blood Cells
Key Takeaways Acute leukemia is a fast-progressing bone marrow cancer in which immature cells called blasts crowd out normal blood production, causing anemia, infections, and bleeding within days to weeks. AML and ALL differ by cell lineage: AML arises from myeloid...
by MH Team | Oct 9, 2023 | Lab Protocols, Red Blood Cells
Procedure At A Glance Perls’ Prussian blue stain is used to histochemically detect and visualize ferric iron (Fe3+) deposits in cells and tissues. Fix slides in absolute methanol for 10 minutes and dry. Submerge slides in the working solution (2% potassium...
by MH Team | Oct 9, 2023 | Lab Protocols, Red Blood Cells
Procedure At-A-Glance The Leishman stain is used in microscopy to differentiate types of blood cells and to detect blood parasites in peripheral blood smears. Flood Slide Protocol Prepare 0.066 M phosphate buffer at pH 6.8. Cover the smear with Leishman stain. Wait...
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