Antibody Screening

Antibody Screening

Introduction  Antibody screening, a cornerstone of blood transfusion safety, aims to detect clinically significant unexpected red blood cell (RBC) antibodies in a patient’s plasma or serum. These antibodies can develop through various mechanisms, including...
Thrombosis: An Overview

Thrombosis: An Overview

Introduction Thrombosis refers to the formation of a blood clot (thrombus) inside a blood vessel. These clots can partially or completely block blood flow, leading to serious health consequences like tissue death, organ damage, and functional impairment. Sometimes,...
Coagulation (Clotting) Disorders

Coagulation (Clotting) Disorders

Introduction Coagulation disorders are a group of conditions that disrupt the body’s normal blood clotting process. This disruption can manifest in two main ways: Increased Bleeding Tendency: This occurs when the blood has difficulty forming clots or the clots...
Platelet Function Disorders

Platelet Function Disorders

Introduction Platelet function disorders are a group of conditions that impair the ability of platelets to clump together (aggregate) and form blood clots. Platelets are blood cells that are essential for stopping bleeding by forming plugs at the site of injury. When...
Thrombocytopenia

Thrombocytopenia

Introduction  Thrombocytopenia is a condition characterized by an abnormally low level of platelets in the blood. In medical terms, a platelet count that falls below 150,000 platelets per microliter is generally considered thrombocytopenia. The physiological role...