Antibody Screening

Antibody Screening

Introduction  Antibody screening, a cornerstone of blood transfusion safety, aims to detect clinically significant unexpected red blood cell (RBC) antibodies in a patient’s plasma or serum. These antibodies can develop through various mechanisms, including...
Thrombosis: An Overview

Thrombosis: An Overview

Key Takeaways Thrombosis are blood clots forming in blood vessels, blocking blood flow. It can occur in the veins (venous thrombosis) or arteries (arterial thrombosis). What causes it? ▾ Inherited factors (genetic mutations) – increase risk but not always...
Coagulation (Clotting) Disorders

Coagulation (Clotting) Disorders

Key Takeaways Blood coagulation (clotting) disorders affect how blood clots, leading to either excessive bleeding or inappropriate clot formation within blood vessels. Types ▾ Inherited: Caused by genetic mutations affecting clotting factors (e.g., hemophilia...
Platelet Function Disorders

Platelet Function Disorders

Key Takeaways Platelet function disorders disrupt the ability of platelets to clump together (aggregate) and form a proper clot. Platelets are blood cells essential for forming clots and stopping bleeding. Causes ▾ Inherited: Caused by genetic mutations...
Thrombocytopenia

Thrombocytopenia

Key Takeaways Thrombocytopenia is a condition characterized by an abnormally low platelets in the blood (generally below 150,000 platelets per microliter).  Causes ▾ Decreased Platelet Production: Bone marrow disorders, vitamin deficiencies, medications,...
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