by MyH Editorial Team | Feb 29, 2024 | White Blood Cells
Key Takeaways Primary myelofibrosis is a rare chronic blood cancer originating in the bone marrow. Characterized by abnormal blood cell production, bone marrow fibrosis (scarring), and enlarged spleen. Pathogenesis ▾: Caused by clonal mutations in a...
by MyH Editorial Team | Feb 29, 2024 | White Blood Cells
Key Takeaways Essential thrombocythemia is a chronic blood cancer (specifically a myeloproliferative neoplasm) in which the bone marrow produces too many platelets, raising the risk of both clots and bleeding [1]. Pathogenesis ▾:Primarily driven by mutations in...
by MyH Editorial Team | Feb 28, 2024 | White Blood Cells
Key Takeaways Polycythemia vera is a chronic blood cancer of the bone marrow that produces too many red blood cells, and often too many platelets and white cells as well. Roughly 95–97% of cases are driven by a mutation in the JAK2 gene [1]. Symptoms ▾:...
by MyH Editorial Team | Feb 27, 2024 | White Blood Cells
Key Takeaways A myeloproliferative neoplasm is a chronic blood cancer in which bone marrow makes too many mature blood cells — red cells, white cells, platelets, or a combination. The three classical BCR::ABL1-negative MPNs are essential thrombocythemia (ET),...
by MyH Editorial Team | Feb 24, 2024 | White Blood Cells
Key Takeaways Leukemia is a cancer of the blood and bone marrow caused by genetic changes in blood-forming stem cells, which lead to uncontrolled growth of abnormal cells called blasts [1,2]. Classifications ▾: The four main types of leukemia are acute...
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