Primary Immune Thrombocytopenia or Primary ITP

Primary Immune Thrombocytopenia or Primary ITP

Key Takeaways Primary Immune Thrombocytopenia also known as Primary ITP is an autoimmune disorder characterized by a low platelet count (thrombocytopenia). Causes ▾: The immune system mistakenly attacks and destroys healthy platelets. The exact trigger for this...
Disseminated Intravascular Coagulation (DIC)

Disseminated Intravascular Coagulation (DIC)

Key Takeaways Disseminated intravascular coagulation (DIC) is a condition with widespread activation of coagulation and fibrinolytic pathways as a secondary complication causing generalized hemorrhage and thrombosis. Causes ▾: Hypersensitivity reactions...
Sickle Cell Anemia

Sickle Cell Anemia

Key Takeaways Sickle cell anemia is a hereditary chronic hemolytic anemia caused by the production of Hb S (a qualitative hemoglobin defect due to a β-globin gene codon 6 mutation [glutamic acid → valine]). Pathophysiology ▾: Sickle cell anemia is...
Components of Donated Blood Products

Components of Donated Blood Products

Key Takeaways Blood ProductStorage & Shelf LifeIndicationsWhole blood1 – 6℃. Shelf life depends on the anticoagulant: 21 days in CPD, up to 35 days in CPDA-1.Massive transfusion Protocol, major obstetric hemorrhage or blood lossPacked red...
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