Introduction Hereditary hemochromatosis is a genetic disorder that affects the body’s ability to regulate iron metabolism. This leads to excessive iron absorption from the diet, resulting in a buildup of iron in the body’s tissues and organs. Iron is a...
Introduction The discovery of the JAK2 V617F mutation revolutionized our understanding of myeloproliferative neoplasms (MPNs). This single nucleotide change, where a guanine (G) is replaced by a thymine (T) at position 1849 in exon 14 of the JAK2 gene, leads to...
Introduction Sideroblastic anemia is a type of anemia characterized by abnormal iron metabolism within red blood cell precursors. It belongs to a category called refractory anemia, which means the bone marrow has difficulty producing healthy red blood cells. The...
Introduction Macrocytic anemia is a specific type of anemia that combines two conditions: macrocytosis and anemia. Macrocytosis refers to a condition where red blood cells are larger than normal. It’s itself not a disease, but rather an abnormality detected in a...
Introduction Microcytic hypochromic anemia is a type of anemia characterized by red blood cells that have less hemoglobin than normal. Hemoglobin is the protein in red blood cells that carries oxygen throughout the body. When red blood cells lack sufficient...
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