White Blood Cells (WBCs)

White Blood Cells (WBCs)

Key Takeaways White blood cells or WBCs, also known as leukocytes, are the body’s defense system cells. They play a crucial role in the immune response, protecting the body from infections, foreign substances and abnormal cells like cancer cells and...
Primary Myelofibrosis (PMF)

Primary Myelofibrosis (PMF)

Key Takeaways Primary myelofibrosis is a rare chronic blood cancer originating in the bone marrow. Characterized by abnormal blood cell production, bone marrow fibrosis (scarring), and enlarged spleen. Pathogenesis ▾: Caused by clonal mutations in a...
Essential Thrombocythemia (ET)

Essential Thrombocythemia (ET)

Key Takeaways Essential thrombocythemia (ET) is a chronic blood cancer characterized by an abnormal increase in platelet production by the bone marrow, leading to an increased risk of blood clots (thrombosis) and bleeding complications. Pathogenesis ▾:Primarily...
Polycythemia Vera

Polycythemia Vera

Key Takeaways Polycythemia vera is a chronic blood disorder characterized by an increased production of red blood cells. It is caused by genetic mutations in the bone marrow particularly JAK2 mutations. Symptoms ▾: May include fatigue,...
Myeloproliferative Neoplasms (MPNs)

Myeloproliferative Neoplasms (MPNs)

Key Takeaways Myeloproliferative neoplasms (MPNs) are a group of chronic myeloid blood cancers characterized by overproduction of one or more types of blood cells in the bone marrow. Classifications ▾: Essential Thrombocythemia (ET): Increased platelet count...
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