Transfusion Medicine

Serologic Crossmatching

Crossmatching mimics transfusion by mixing recipient serum & donor cells. Clumping (agglutination) indicates incompatibility, preventing transfusion reactions.

Indirect Antiglobulin (Coombs) Test (IAT)

Unmask hidden blood threats! IAT protocol detects antibodies in serum, ensuring safe transfusions & diagnosing immune disorders.

Direct Antiglobulin (Coombs) Test (DAT)

To detect the presence of antibodies or complement proteins bound to red blood cells (RBCs) in vivo, indicating potential immune-mediated hemolysis.