Acute Leukemia
Definition
Signs & Symptoms
Risk Factors
Causes
Peripheral blood characteristics
BM characteristics
Important investigations & related results
Treatment & management
AML |
ALL |
Induction (e.g. vincristine, asparginase, dexamethasone ± daunorubicin) ↓ Consolidation (daunorubicin, cytosine arabinoside, vincristine, etoposide, thioguanine or mercaptopurine, cyclophosphoamide) ↓ Cranial prophylaxis ↓ Maintenance therapy (e.g. mercaptopurine, methotrexate, vincristine, dexamethasone) ↓ Late intensification ↓ Maintenance therapy |
Induction (daunorubicin, cytosine arabinoside, etoposide) ↓ Consolidation (daunorubicin, cytosine arabinoside, etoposide) ↓ Consolidation (m-AMSA, etoposide, cytosine arabinoside) ↓ Possible stem cell transplantation / further consolidation (mitoxantrone, idarubicin, high dose cytosine arabinoside) |

Acute lymphoblastic leukemia x 400

Acute myeloid leukemia x 400

Bone marrow aspirate with positive myeloperoxidase stain in AML x 400
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