Hepatomegaly means an enlarged liver, often a sign of underlying conditions like hepatitis, fatty liver, or heart failure. Diagnosis involves physical exams and imaging.
Evans Syndrome
Evans syndrome: Rare autoimmune disorder causing low red blood cells & platelets (AIHA & ITP). Can lead to fatigue, bruising, and bleeding.
Wilson’s Disease
Wilson’s disease: A rare genetic disorder causing toxic copper buildup in the liver and brain. Early diagnosis and lifelong treatment are crucial.

Liver and Causes of Hepatomegaly
Hepatomegaly means an enlarged liver, often a sign of underlying conditions like hepatitis, fatty liver, or heart failure. Diagnosis involves physical exams and imaging.

Evans Syndrome
Evans syndrome: Rare autoimmune disorder causing low red blood cells & platelets (AIHA & ITP). Can lead to fatigue, bruising, and bleeding.

Hemoglobinuria: Overview and Causes
Hemoglobinuria: Red urine from free hemoglobin, not whole RBCs. Signals serious issues like hemolysis. Prompt diagnosis is vital.
Hemolytic Uremic Syndrome (HUS)
Hemolytic uremic syndrome (HUS): A rare but serious condition causing red blood cell damage, low platelets, and kidney failure. Early diagnosis is key.
Hemoglobinuria: Overview and Causes
Hemoglobinuria: Red urine from free hemoglobin, not whole RBCs. Signals serious issues like hemolysis. Prompt diagnosis is vital.
Hematuria (Blood in Urine): Overview & Causes
Hematuria: Blood in urine, gross (visible) or microscopic. Could signal infection, stones, or more serious issues.
Paroxysmal Cold Hemoglobinuria
Paroxysmal cold hemoglobinuria (PCH) is a rare autoimmune anemia. Cold exposure triggers red cell destruction, causing dark urine, back pain, and chills. Diagnosis relies on the Donath-Landsteiner test.
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Paroxysmal nocturnal hemoglobinuria (PNH): An acquired blood disease where the immune system attacks red cells due to a mutation in the X chromosome.
Warm Autoimmune Hemolytic Anemia (warm AIHA)
Warm AIHA: Immune system attacks red blood cells, causing anemia. Symptoms include fatigue, pallor, and jaundice. Treatment targets immune suppression.