by MH Team | Apr 19, 2024 | Lab Protocols, White Blood Cells
Introduction The discovery of the JAK2 V617F mutation revolutionized our understanding of myeloproliferative neoplasms (MPNs). This single nucleotide change, where a guanine (G) is replaced by a thymine (T) at position 1849 in exon 14 of the JAK2 gene, leads to...
by MH Team | Apr 10, 2024 | Red Blood Cells
Key Takeaways Sideroblastic anemia is a group of inherited and acquired disorders in which bone marrow cells cannot build iron into hemoglobin, leaving iron stranded inside red cell precursors as ring sideroblasts visible on Prussian blue staining [3,9]. Causes...
by MH Team | Apr 9, 2024 | Red Blood Cells
Key Takeaways Macrocytic anemia is defined by the presence of abnormally large red blood cells, indicated by a Mean Corpuscular Volume (MCV) strictly greater than 100 fL. Categories: Megaloblastic (caused by impaired DNA synthesis) or non-megaloblastic (caused by...
by MH Team | Apr 8, 2024 | Red Blood Cells
Key Takeaways Hypochromic Microcytic Anemia is a condition where red blood cells are smaller than normal (microcytosis) and contain less hemoglobin, making them paler (hypochromia). Primary Causes ▾: Iron Deficiency Anemia (IDA) ▾: The most common cause,...
by MH Team | Apr 5, 2024 | Red Blood Cells
Key Takeaways Anemia of Chronic Disease also known as Anemia of Inflammation is a type of anemia that develops as a consequence of chronic inflammatory conditions in the body. Causes ▾: Chronic infections Autoimmune diseases Other chronic inflammatory...
Recent Comments