by MyH Editorial Team | Nov 22, 2023 | Red Blood Cells
Key Takeaways Anemia is a reduction in red blood cells or hemoglobin that lowers the blood’s oxygen-carrying capacity. It is a sign of an underlying problem, not a disease in itself [1,3]. Anemia Symptoms and Factors Affecting Them ▾: Symptoms vary based...
by MyH Editorial Team | Nov 14, 2023 | Red Blood Cells
Key Takeaways A red blood cell (RBC, or erythrocyte) is a biconcave, anucleate cell whose central job is to ferry oxygen from the lungs to tissues and carbon dioxide back to the lungs. About 1.9 billion people worldwide live with anemia, making red blood cell...
by MyH Editorial Team | Nov 14, 2023 | Lab Protocols, Red Blood Cells
Procedure-at-a-Glance A PCR protocol for the beta-globin (HBB) gene amplifies the entire 1.6 kb gene so it can be sequenced and screened for mutations that cause beta thalassemia. Thaw reagents and UV-sterilize the workstation. Make a master mix by combining...
by MyH Editorial Team | Nov 13, 2023 | Transfusion Medicine
Key Takeaways The ABO blood group is the most clinically important blood group system in transfusion and organ transplantation. A mismatch can trigger acute intravascular hemolysis, kidney failure, and death within minutes. Three antigens define the system: A, B, and...
by MyH Editorial Team | Nov 9, 2023 | Lab Protocols, White Blood Cells
Procedure-at-a-Glance The leukocyte alkaline phosphatase (LAP) stain, also called the neutrophil alkaline phosphatase (NAP) stain, is a cytochemical test that measures the enzyme alkaline phosphatase inside mature neutrophils. Fix fresh smears in Cold...
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