by MyH Editorial Team | Nov 28, 2023 | Lab Protocols, Red Blood Cells
Procedure At-A-Glance HPLC, or high performance liquid chromatography, is the most widely used laboratory method for screening hemoglobinopathies such as beta-thalassemia trait, sickle cell disease, and HbE disease [1,5]. The protocol below describes the Bio-Rad...
by MyH Editorial Team | Nov 23, 2023 | Lab Protocols, Red Blood Cells
Procedure At-A-Glance The G6PD test screens for glucose-6-phosphate dehydrogenase deficiency, the most common inherited enzyme disorder, affecting around 400 million people worldwide [3]. The fluorescent spot test (FST) is a fast, low-cost qualitative G6PD test that...
by MyH Editorial Team | Nov 22, 2023 | Red Blood Cells
Key Takeaways Anemia is a reduction in red blood cells or hemoglobin that lowers the blood’s oxygen-carrying capacity. It is a sign of an underlying problem, not a disease in itself [1,3]. Anemia Symptoms and Factors Affecting Them ▾: Symptoms vary based...
by MyH Editorial Team | Nov 14, 2023 | Red Blood Cells
Key Takeaways A red blood cell (RBC, or erythrocyte) is a biconcave, anucleate cell whose central job is to ferry oxygen from the lungs to tissues and carbon dioxide back to the lungs. About 1.9 billion people worldwide live with anemia, making red blood cell...
by MyH Editorial Team | Nov 14, 2023 | Lab Protocols, Red Blood Cells
Procedure-at-a-Glance A PCR protocol for the beta-globin (HBB) gene amplifies the entire 1.6 kb gene so it can be sequenced and screened for mutations that cause beta thalassemia. Thaw reagents and UV-sterilize the workstation. Make a master mix by combining...
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