Dengue & Thrombocytopenia

Dengue & Thrombocytopenia

Key Takeaways Dengue is a mosquito-borne viral infection caused by four serotypes (DENV-1 to DENV-4) and spread mainly by Aedes aegypti mosquitoes; in 2024, WHO recorded over 14 million cases worldwide, the highest on record [1,7]. Thrombocytopenia (a low platelet...
Systemic Approach to Anemia

Systemic Approach to Anemia

Key Takeaways Anemia is a sign, not a diagnosis. A systematic approach to anemia means finding the underlying cause before treating it, because iron, B12, kidney disease, inflammation, and inherited disorders each need a different plan. Detailed Clinical History...
Hereditary Hemochromatosis

Hereditary Hemochromatosis

Key Takeaways Hereditary hemochromatosis is a genetic disorder of iron regulation that causes progressive iron overload in organs and tissues. Causes ▾: Most cases involve HFE gene mutations (C282Y/H63D); inheritance is autosomal recessive. Symptoms ▾:...
Sideroblastic Anemia

Sideroblastic Anemia

Key Takeaways Sideroblastic anemia is a group of inherited and acquired disorders in which bone marrow cells cannot build iron into hemoglobin, leaving iron stranded inside red cell precursors as ring sideroblasts visible on Prussian blue staining [3,9]. Causes...
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