by MyH Editorial Team | Dec 5, 2023 | White Blood Cells
Key Takeaways Acute myeloid leukemia or AML is an aggressive blood cancer in which the bone marrow makes too many immature myeloid cells (blasts) that cannot mature into working red cells, white cells, or platelets. Predisposing factors ▾: DNA damaging agents...
by MyH Editorial Team | Dec 1, 2023 | Lab Protocols, Transfusion Medicine
Procedure At A Glance The ABO Rh test identifies a person’s ABO group (A, B, AB, or O) and RhD type (positive or negative), and it is the single most important pre-transfusion test in any blood bank [1]. Key Steps ▾ Prepare a 2–5% red cell...
by MyH Editorial Team | Nov 29, 2023 | Red Blood Cells
Key Takeaways Alpha thalassemia is an inherited blood disorder in which one or more of the four alpha-globin genes is missing or faulty, reducing the alpha-globin protein needed to build normal hemoglobin [1]. Epidemiology ▾: It follows an autosomal recessive...
by MyH Editorial Team | Nov 28, 2023 | Lab Protocols, Red Blood Cells
Procedure At-A-Glance HPLC, or high performance liquid chromatography, is the most widely used laboratory method for screening hemoglobinopathies such as beta-thalassemia trait, sickle cell disease, and HbE disease [1,5]. The protocol below describes the Bio-Rad...
by MyH Editorial Team | Nov 23, 2023 | Lab Protocols, Red Blood Cells
Procedure At-A-Glance The G6PD test screens for glucose-6-phosphate dehydrogenase deficiency, the most common inherited enzyme disorder, affecting around 400 million people worldwide [3]. The fluorescent spot test (FST) is a fast, low-cost qualitative G6PD test that...
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