Essential Thrombocythemia (ET)

Essential Thrombocythemia (ET)

Key Takeaways Essential thrombocythemia is a chronic blood cancer (specifically a myeloproliferative neoplasm) in which the bone marrow produces too many platelets, raising the risk of both clots and bleeding [1]. Pathogenesis ▾:Primarily driven by mutations in...
Polycythemia Vera

Polycythemia Vera

Key Takeaways Polycythemia vera is a chronic blood cancer of the bone marrow that produces too many red blood cells, and often too many platelets and white cells as well. Roughly 95–97% of cases are driven by a mutation in the JAK2 gene [1]. Symptoms ▾:...
Myeloproliferative Neoplasms (MPNs)

Myeloproliferative Neoplasms (MPNs)

Key Takeaways A myeloproliferative neoplasm is a chronic blood cancer in which bone marrow makes too many mature blood cells — red cells, white cells, platelets, or a combination. The three classical BCR::ABL1-negative MPNs are essential thrombocythemia (ET),...
Leukemia: An Overview

Leukemia: An Overview

Key Takeaways Leukemia is a cancer of the blood and bone marrow caused by genetic changes in blood-forming stem cells, which lead to uncontrolled growth of abnormal cells called blasts [1,2]. Classifications ▾: The four main types of leukemia are acute...
Lymphoma

Lymphoma

Key Takeaways Lymphoma is a cancer of lymphocytes and is grouped into Hodgkin lymphoma and non-Hodgkin lymphoma based on whether a specific abnormal cell, the Reed-Sternberg cell, is present [2]. Signs & symptoms ▾: The most common first sign is a painless...
Secret Link