by MH Team | Nov 9, 2023 | Lab Protocols, White Blood Cells
Procedure-at-a-Glance StepActionDuration1. FixationFix fresh smears in Cold Formalin-Methanol (0-10°C).30 Seconds2. WashingGently rinse with running tap water and air dry.—3. IncubationImmerse in freshly prepared buffered substrate.15–30 Minutes4....
by MH Team | Nov 9, 2023 | Red Blood Cells
Key Takeaways Aplastic anemia (AA) causes pancytopenia (reduction of all blood cell types: RBCs, WBCs and platelets) due to aplasia (failure) of the bone marrow to function (to produce blood cells). Causes▾: Congenital e.g. Fanconi anemia, dyskeratosis...
by MH Team | Nov 3, 2023 | Platelet Disorders
Key Takeaways Thrombotic thrombocytopenic purpura (TTP) is a type of thrombocytopenia due to deficiency of ADAMTS13 metalloprotease which leads to formation of platelet thrombi in microvessels. Signs and symptoms (pentad) ▾: Thrombocytopenia...
by MH Team | Nov 3, 2023 | White Blood Cells
Key Takeaways T-cell ALL, or T-cell Acute Lymphoblastic Leukemia, is an aggressive hematologic malignancy resulting from the clonal expansion of immature T-cell precursors (lymphoblasts) that have failed to differentiate in the thymus. Epidemiology: Accounts for...
by MH Team | Nov 2, 2023 | White Blood Cells
Key Takeaways B-cell ALL, or B-cell Acute Lymphoblastic Leukemia, is an aggressive malignancy of immature B-cell precursors or lymphoblasts in the bone marrow. Demographics: Most common childhood cancer; has a bimodal age distribution (peaks at <5 and >65...
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