by MH Team | Jan 8, 2024 | Platelet Disorders
Key Takeaways The coagulation cascade is a complex series of biochemical reactions that occur in the blood when a vessel is injured. It’s a tightly regulated process that involves numerous proteins, called coagulation factors, working together to form a blood...
by MH Team | Jan 5, 2024 | Lab Protocols, Transfusion Medicine
Procedure At a Glance Prepare Patient Sample: Centrifuge patient serum to obtain plasma/serum. Prepare Red Blood Cells (RBCs): Make a 2-5% suspension of donor or reagent RBCs in normal saline. Combine Serum & RBCs: Add patient serum to the prepared RBC suspension....
by MH Team | Dec 31, 2023 | Lab Protocols, Transfusion Medicine
Procedure At a Glance The purpose of the Direct Antiglobulin (Coombs) Test or DAT procedure is to detect in vivo sensitization of red blood cells with antibodies or complement components. Collect Patient Sample: Obtain an anticoagulated blood sample (e.g., in an EDTA...
by MH Team | Dec 30, 2023 | Platelet Disorders
Key Takeaways Primary hemostasis is the body’s rapid response to a broken blood vessel in the physiology of hemostasis, forming a platelet plug through platelet adhesion and platelet aggregation before the secondary hemostasis (coagulation cascade) kicks...
by MH Team | Dec 27, 2023 | Platelet Disorders
Key Takeaways Venous thromboembolism or also known as VTE is a condition where a blood clot (thrombosis) forms in a deep vein, usually in the leg (deep vein thrombosis) or pelvis, and can travel to the lungs, causing a pulmonary embolism. This is a serious condition...
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