by MyH Editorial Team | Jan 11, 2024 | Hemostasis Disorders
Key Takeaways Fibrinolysis is the enzyme-driven process that dissolves a blood clot once it has done its job, restoring blood flow and preventing dangerous clot extension. Essential Players ▾: The central enzyme is plasmin, made on demand from circulating...
by MyH Editorial Team | Jan 8, 2024 | Hemostasis Disorders
Key Takeaways The coagulation cascade is the second stage of hemostasis. Once platelets form their initial plug, clotting factors weave a fibrin mesh that locks the plug in place and seals the injury. Two pathways ▾: Two pathways feed into a common pathway. The...
by MyH Editorial Team | Jan 5, 2024 | Lab Protocols, Transfusion Medicine
Procedure At a Glance The indirect antiglobulin test (IAT), also called the indirect Coombs test, detects free IgG antibodies in plasma that could bind red blood cells [1,3]. Spin the patient sample to obtain clear serum or plasma. Prepare reagent red cells at a...
by MyH Editorial Team | Dec 31, 2023 | Lab Protocols, Transfusion Medicine
Procedure At a Glance The Direct Antiglobulin Test or also known as DAT is the cornerstone laboratory test for diagnosing autoimmune hemolytic anemia, drug-induced immune hemolytic anemia, hemolytic disease of the fetus and newborn, and hemolytic transfusion reactions...
by MyH Editorial Team | Dec 30, 2023 | Hemostasis Disorders
Key Takeaways Primary hemostasis is the body’s rapid first response to a damaged blood vessel, forming a temporary platelet plug within minutes to stop bleeding before the coagulation cascade takes over. The Steps in Primary Hemostasis ▾: The four steps...
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