Acute Promyelocytic Leukemia (APL)

Acute Promyelocytic Leukemia (APL)

Key Takeaways Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia driven by the t(15;17) translocation, which creates the PML-RARA fusion gene and blocks white blood cells from maturing. Symptoms ▾: Patients typically present with the...
Copper Deficiency

Copper Deficiency

Key Takeaways Copper deficiency is an under-recognized cause of cytopenias and neurological disease, with the classic triad of anemia, neutropenia, and myeloneuropathy [1,3]. Causes ▾: The commonest causes are bariatric and upper gastrointestinal surgery,...
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