by MyH Editorial Team | Apr 24, 2026 | White Blood Cells
Key Takeaways Systemic Mastocytosis is a clonal myeloproliferative neoplasm characterized by the abnormal accumulation of neoplastic mast cells in extracutaneous organs, most commonly the bone marrow. Molecular Driver ▾: The KIT D816V somatic mutation is the...
by MyH Editorial Team | Apr 7, 2026 | Red Blood Cells
Key Takeaways Acute Intermittent Porphyria or AIP is an autosomal dominant hepatic disorder causing acute neurovisceral crises without cutaneous symptoms. Etiology ▾: HMBS gene mutations triggered by porphyrinogenic drugs, progesterone, or caloric restriction....
by MyH Editorial Team | Mar 30, 2026 | White Blood Cells
Key Takeaways Langerhans Cell Histiocytosis or formerly known as Histiocytosis X is a clonal myeloid neoplasm characterized by the proliferation of abnormal cells resembling Langerhans cells. It is driven by inflammatory signaling rather than simple cell mass....
by MyH Editorial Team | Mar 25, 2026 | White Blood Cells
Key Takeaways Tumor Lysis Syndrome or TLS is a life-threatening oncologic emergency caused by the rapid, massive lysis of malignant cells. This releases intracellular contents (potassium, phosphorus, and nucleic acids) into the systemic circulation, overwhelming...
by MyH Editorial Team | Mar 17, 2026 | White Blood Cells
Key Takeaways Hemophagocytic Lymphohistiocytosis or HLH is a life-threatening “cytokine storm” where a broken “off-switch” in the immune system leads to unchecked, hyperactive T-cells and macrophages that attack the patient’s own...
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