by MH Team | Oct 23, 2023 | Hemostasis Disorders
Key Takeaways Primary immune thrombocytopenia (ITP) is an acquired autoimmune disorder in which the immune system both destroys platelets and slows their production, dropping the platelet count below 100 × 10⁹/L with no other cause found [1,2]. Symptoms...
by MH Team | Oct 20, 2023 | Hemostasis Disorders
Key Takeaways Disseminated intravascular coagulation is an acquired, life-threatening disorder where systemic clot formation, disordered fibrinolysis, and blood vessel injury happen at once, leading to both microthrombi and bleeding [1]. Causes ▾:Disseminated...
by MH Team | Oct 19, 2023 | Red Blood Cells
Key Takeaways G6PD deficiency is the most common inherited enzyme defect of red blood cells, affecting an estimated 400 million people worldwide [4]. Most carriers are healthy until something triggers oxidative stress. G6PD deficiency symptoms & signs ▾: It...
by MH Team | Oct 19, 2023 | Red Blood Cells
Key Takeaways Sickle cell disease (SCD) is a group of inherited blood disorders, not a single condition. All forms involve hemoglobin S (HbS), produced by a mutation in codon 6 of the β-globin gene that swaps glutamic acid for valine. Pathophysiology ▾:...
by MH Team | Oct 18, 2023 | Transfusion Medicine
Key Takeaways Blood ProductStorage & Shelf LifeIndicationsWhole blood1 – 6℃. Shelf life depends on the anticoagulant: 21 days in CPD, up to 35 days in CPDA-1.Massive transfusion Protocol, major obstetric hemorrhage or blood lossPacked red...
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