Acute Hemolytic Transfusion Reaction

Acute Hemolytic Transfusion Reaction

Key Takeaways Acute Hemolytic Transfusion Reaction (AHTR) is an acute hemolysis due to the administration of antigenically incompatible red cells.  Timing ▾: During transfusion or within 24 hours. Signs and Symptoms ▾: Fever and chills Back or flank...
Multiple Myeloma

Multiple Myeloma

Key Takeaways Multiple myeloma is a cancer of plasma cells, a type of white blood cell that produces antibodies. In this condition, abnormal plasma cells multiply uncontrollably and accumulate in the bone marrow. It is slightly more common in males than females and...
Hemophilia

Hemophilia

Key Takeaways Hemophilia, the most common severe, inherited bleeding disorder, represents a failure in the secondary hemostatic mechanism. It is an X-linked recessive disorder characterized by a deficiency or dysfunction of a specific plasma coagulation factor,...
Vitamin K Deficiency Bleeding (VKDB)

Vitamin K Deficiency Bleeding (VKDB)

Key Takeaways Vitamin K Deficiency Bleeding (VKDB) is a hemorrhagic disorder in newborns and infants (typically 0-6 months) caused by insufficient levels of vitamin K-dependent clotting factors, leading to spontaneous or traumatic bleeding. Causes: All newborns are...
Von Willebrand Disorder (VWD)

Von Willebrand Disorder (VWD)

Key Takeaways Von Willebrand Disorder also known as Von Willebrand Disease or VWD is an inherited coagulation disorder caused by mutations in the Von Willebrand Factor (VWF). VWF is a factor VIII carrier protein and mediates platelet adhesion to the endothelium....
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