Glucose-6-phosphate dehydrogenase (G6PD) deficiency

Signs & Symptoms

Usually asymptomatic. Acute hemolysis with hemoglobinuria in response to oxidative stress, neonatal jaundice.

Risk Factors

Mainly West Africans, Mediterraneans, Middle Easterns and Southeast Asians.



Peripheral blood characteristics

In crises: contracted and fragmented cells, bite cells and blister cell with Heinz bodies.

Important investigations & related results

Direct enzyme assay on red cells.

Treatment & management

Treat underlying cause. Blood transfusion for severe anemia.

View our Upcoming Products

To facilitate the learning of our students we have developed a number of products that are due for release soon. These include a Practical Manual for Medical Undergraduates and two boardgames.