by MyH Editorial Team | Oct 15, 2023 | Transfusion Medicine
Key Takeaways Hemolytic Disease of the Fetus and Newborn is caused by maternal IgG antibodies crossing the placenta and destroying fetal red blood cells, most often due to RhD incompatibility, with anti-Kell and ABO as the next most important triggers. Pathophysiology...
by MyH Editorial Team | Oct 9, 2023 | Lab Protocols, White Blood Cells
Procedure-At-A-Glance Myeloperoxidase is an enzyme inside the granules of neutrophils and other myeloid cells. It is the most specific cytochemical marker of myeloid lineage [3,4]. The myeloperoxidase stain helps separate acute myeloid leukemia (AML), where blasts are...
by MyH Editorial Team | Oct 9, 2023 | Lab Protocols, White Blood Cells
Procedure-At-A-Glance May-Grünwald Giemsa (MGG) is a two-step Romanowsky stain used worldwide for blood smears, bone marrow aspirates, and cytology samples, and is recommended by the ICSH for bone marrow morphology. Fix the bone marrow aspirate smear in absolute...
by MyH Editorial Team | Oct 9, 2023 | White Blood Cells
Key Takeaways Hodgkin Lymphoma or formerly known as Hodgkin’s disease is a heterogeneous group of disorders caused by malignant lymphocytes presenting as lymphadenopathy and defined by Reed-Sternberg cells. Hodgkin lymphoma signs and symptoms ▾: The most...
by MyH Editorial Team | Oct 9, 2023 | White Blood Cells
Key Takeaways Chronic myeloid leukemia is a slow-growing blood cancer caused by the BCR-ABL1 fusion gene on the Philadelphia chromosome, formed by a swap between chromosomes 9 and 22. Pathogenesis ▾: Signs and symptoms ▾: Most patients are diagnosed in...
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