May Grunwald Giemsa (MGG) Staining

May Grunwald Giemsa (MGG) Staining

Introduction Similar to the Leishman stain, MGG is part of the Romanowsky stains and adopts the same principle. MGG stain consists of May-Grünwald stain and Giemsa stain. MGG stain is used for morphology assessment of bone marrow aspirates especially in diseases like...
Hodgkin Lymphoma & Reed-Sternberg

Hodgkin Lymphoma & Reed-Sternberg

TL;DR Hodgkin Lymphoma is a heterogeneous group of disorders caused by malignant lymphocytes that accumulate in lymph nodes presenting as lymphadenopathy. Hodgkin Lymphoma (HL) is differentiated from non-Hodgkin lymphoma by presence of Reed-Sternberg (RS) cells and a...
Chronic Myeloid Leukemia (CML)

Chronic Myeloid Leukemia (CML)

TL;DR Chronic myeloid leukemia (CML) is a slower progressing clonal disorder of the hematopoietic stem cells where untreated patients progress to blast crisis stage after 3 – 5 years. It has a peak incidence at 40 – 60 years old. Signs and symptoms ▾...
Chronic Lymphocytic Leukemia (CLL)

Chronic Lymphocytic Leukemia (CLL)

TL;DR Chronic lymphocytic leukemia (CLL) is a slow progressing cancer due to overgrowth and accumulation of small incompetent mature-looking B-lymphocytes in the blood, bone marrow and lymphoid tissues. Small lymphocytic leukemia is a different clinical manifestation...