by MH Team | Oct 20, 2023 | Platelet Disorders
TL;DR Definition ▾ Widespread activation of coagulation and fibrinolytic pathways as a secondary complication causing generalized hemorrhage and thrombosis. Causes ▾ Hypersensitivity reactions Incompatible transfusion reaction Incompatible organ transplantation...
by MH Team | Oct 19, 2023 | Red Blood Cells
TL;DR Definition ▾ G6PD deficiency anemia is an inherited hemolytic anemia due to red cell enzyme defect. X-linked recessive disorder – full expression only seen in males. G6PD deficiency symptoms & signs ▾ Usually asymptomatic Acute intravascular hemolytic...
by MH Team | Oct 19, 2023 | Red Blood Cells
TL;DR Definition ▾ Sickle cell anemia is a hereditary chronic hemolytic anemia caused by the production of Hb S (a qualitative hemoglobin defect due to a β-globin gene codon 6 mutation [glutamic acid → valine]) Pathophysiology ▾ Sickle cell anemia is a genetic...
by MH Team | Oct 18, 2023 | Transfusion Medicine
TL;DR ExpiryStorageTransportExpiryIndicationsWhole bloodIn a blood bank refrigerator at 2℃ – 6℃Can be transported for the next 24h if maintained at 1℃ – 10℃ during transportation35 days in a closed system, 24 hr in an open systemAcute blood lossExchange...
by MH Team | Oct 18, 2023 | Transfusion Medicine
TL;DR Definition ▾ Acute hemolytic transfusion reaction is an acute hemolysis due to the administration of antigenically incompatible red cells. Timing ▾ During transfusion or within 24 hours. Signs and Symptoms ▾ Fever: Often the first sign, occurring within minutes...
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