by MH Team | Jan 27, 2024 | Platelet Disorders
TL;DR Deep vein thrombosis (DVT) is a blood clot (thrombosis) that forms in deep leg veins, often due to slow blood flow or injury. Causes ▾: Slow blood flow (stasis), vessel wall damage, and hypercoagulability (increased clotting tendency). Risks ▾: Sitting for...
by MH Team | Jan 20, 2024 | Lab Protocols, Red Blood Cells
Introduction Unraveling the mysteries of life often requires peering into the microscopic world of DNA. Conventional Polymerase Chain Reaction (PCR) is a powerful technique that allows us to amplify specific DNA sequences, making them visible and easily analyzed for...
by MH Team | Jan 18, 2024 | Commentaries, rbc
Introduction SCD arises from a single nucleotide mutation in the beta-globin gene (HBB) on chromosome 11. This mutation leads to the substitution of valine for glutamic acid at the sixth amino acid position of the beta-globin chain in the hemoglobin molecule. This...
by MH Team | Jan 16, 2024 | Lab Protocols, Red Blood Cells
Introduction The sickle cell test, also known as the dithionite solubility test, is a simple and rapid method used to detect the presence of sickle cell disease or sickle cell trait. Sickle cell disease (SCD) is a group of inherited blood disorders characterized by...
by MH Team | Jan 11, 2024 | Platelet Disorders
TL;DR Key Function of Fibrinolysis: Dissolves fibrin clots after wound healing, restoring blood flow and preventing unwanted thrombus formation. Essential Players ▾ Plasminogen: The inactive precursor protein, waiting to be activated. Plasmin: The active enzyme...
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