by MyH Editorial Team | May 1, 2024 | Red Blood Cells
Key Takeaways Systemic comprehensive approach to anemia ensures thorough evaluation, leading to an accurate diagnosis and the most appropriate treatment plan for the specific type of anemia. It also avoids unnecessary investigations and treatments, ultimately...
by MyH Editorial Team | Apr 23, 2024 | Red Blood Cells
Key Takeaways Hereditary hemochromatosis is a genetic disorder of iron regulation that causes progressive iron overload in organs and tissues. Causes ▾: Most cases involve HFE gene mutations (C282Y/H63D); inheritance is autosomal recessive. Symptoms ▾:...
by MyH Editorial Team | Apr 19, 2024 | Lab Protocols, White Blood Cells
Introduction The discovery of the JAK2 V617F mutation revolutionized our understanding of myeloproliferative neoplasms (MPNs). This single nucleotide change, where a guanine (G) is replaced by a thymine (T) at position 1849 in exon 14 of the JAK2 gene, leads to...
by MyH Editorial Team | Apr 10, 2024 | Red Blood Cells
Key Takeaways Sideroblastic anemia is a group of inherited and acquired disorders in which bone marrow cells cannot build iron into hemoglobin, leaving iron stranded inside red cell precursors as ring sideroblasts visible on Prussian blue staining [3,9]. Causes...
by MyH Editorial Team | Apr 9, 2024 | Red Blood Cells
Key Takeaways Macrocytic anemia is defined by the presence of abnormally large red blood cells, indicated by a Mean Corpuscular Volume (MCV) strictly greater than 100 fL. Categories: Megaloblastic (caused by impaired DNA synthesis) or non-megaloblastic (caused by...
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