by MH Team | Oct 16, 2023 | Platelet Disorders
TL;DR Von Willebrand Disorder also known as Von Willebrand Disease or VWD is an inherited coagulation disorder caused by mutations in the Von Willebrand Factor (VWF). VWF is a factor VIII carrier protein and mediates platelet adhesion to the endothelium. Pathogenesis...
by MH Team | Oct 15, 2023 | Transfusion Medicine
TL;DR Hemolytic disease of the fetus and newborn (HDFN) also known as erythroblastosis fetalis is an allo-immune hemolytic anemia in the fetus or newborn. This is due to a fetal-maternal incompatibility for one of the red cell blood group systems i.e. Rh blood group...
by MH Team | Oct 9, 2023 | Lab Protocols, White Blood Cells
Procedure-At-A-Glance The myeloperoxidase reaction (MPO) stain works by utilizing the peroxidase in leukocyte granules to oxidize a chromogen (like benzidine) in the presence of hydrogen peroxide (H2O2), forming an insoluble, colored reaction product...
by MH Team | Oct 9, 2023 | Lab Protocols, White Blood Cells
Procedure-At-A-Glance The May-Grünwald Giemsa or MGG stain is a type of Romanowsky stain, similar to the Leishman stain, and works on the same principle. It is used for morphology assessment of blood cells, bone marrow aspirates, and cells in body fluids, which...
by MH Team | Oct 9, 2023 | White Blood Cells
TL;DR Hodgkin Lymphoma or formerly known as Hodgkin’s disease is a heterogeneous group of disorders caused by malignant lymphocytes that accumulate in lymph nodes presenting as lymphadenopathy. Hodgkin Lymphoma (Hodgkin’s disease) is differentiated from...
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