Chronic Myeloid Leukemia or CML

Chronic Myeloid Leukemia or CML

TL;DR Chronic Myeloid Leukemia (CML) is a clonal myeloproliferative neoplasm characterized by the excessive and unregulated proliferation of mature and maturing granulocytic cells, primarily affecting the myeloid lineage. Pathogenesis ▾: Signs and symptoms ▾:...
Chronic Lymphocytic Leukemia (CLL)

Chronic Lymphocytic Leukemia (CLL)

TL;DR Chronic lymphocytic leukemia (CLL) is a slow progressing cancer due to overgrowth and accumulation of small incompetent mature-looking B-lymphocytes in the blood, bone marrow and lymphoid tissues. Small lymphocytic leukemia is a different clinical manifestation...
Acute Leukemia: An Overview

Acute Leukemia: An Overview

TL;DR Acute leukemia is an aggressive hematologic malignancy characterized by the rapid, uncontrolled proliferation and accumulation of immature hematopoietic progenitor cells (blasts) in the bone marrow and peripheral blood, leading to the suppression of normal...
Perls’ Prussian Blue Staining

Perls’ Prussian Blue Staining

Procedure At A Glance Perls’ Prussian blue stain is used to histochemically detect and visualize ferric iron (Fe3+) deposits in cells and tissues. Preparation: Select and label positive control and test sample slides. Fix slides in absolute methanol for 10...