by MH Team | Dec 14, 2023 | White Blood Cells
TL;DR Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic malignancies due to impaired maturation of myeloid progenitors leading to cytopenias and dysplasia of myeloid-lineage cells. Peak incidence > 70 years old. Signs and symptoms ▾ Fatigue,...
by MH Team | Dec 11, 2023 | Lab Protocols, Red Blood Cells
Introduction Hemolysate, a suspension of lysed red blood cells, plays a crucial role in both Hb electrophoresis and alkaline denaturation tests. These tests rely on the biochemical properties of hemoglobin to differentiate between different types of hemoglobin and...
by MH Team | Dec 11, 2023 | Lab Protocols, Platelet Disorders
Introduction The activated partial thromboplastin time (APTT) is a coagulation test that measures the intrinsic pathway of blood clotting. While the APTT itself is a valuable diagnostic tool, it can be further enhanced through the use of manual mixing studies. Mixing...
by MH Team | Dec 5, 2023 | White Blood Cells
TL;DR Acute myeloid leukemia (AML) is an aggressive neoplasm of the myeloid lineage caused by acquired somatic defects due to either environmental influences e.g. chemicals, drugs, radiation or infections e.g.bacteria, protozoa in early hematopoietic blasts that...
by MH Team | Dec 1, 2023 | Lab Protocols, Transfusion Medicine
Introduction The ABO and RhD blood groups are two of the most important systems for classifying human blood. They are determined by the presence or absence of specific antigens on the surface of red blood cells. The ABO Blood Group System The ABO blood group system is...
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