TL;DR Hemolytic fetal disease of the newborn (HDN) is an allo-immune hemolytic anemia in the fetus or newborn. This is due to a fetal-maternal incompatibility for one of the red cell blood group systems i.e. Rh group causing maternal IgG to cross the placenta and...
Introduction Myeloperoxidase is a lysosomal enzyme, located in the azurophilic granules of the neutrophils and its precursors, eosinophils and monocytes. This MPO stain is mainly used to differentiate acute myeloid leukaemia from acute lymphoblastic leukaemia. MPO...
Introduction Similar to the Leishman stain, MGG is part of the Romanowsky stains and adopts the same principle. MGG stain consists of May-Grünwald stain and Giemsa stain. MGG stain is used for morphology assessment of bone marrow aspirates especially in diseases like...
TL;DR Hodgkin Lymphoma is a heterogeneous group of disorders caused by malignant lymphocytes that accumulate in lymph nodes presenting as lymphadenopathy. Hodgkin lymphoma is differentiated from non-Hodgkin lymphoma by presence of Reed-Sternberg (RS) cells and a...
TL;DR Chronic myeloid leukemia (CML) is a slower progressing clonal disorder of the hematopoietic stem cells where untreated patients progress to blast crisis stage after 3 – 5 years. It has a peak incidence at 40 – 60 years old. Signs and symptoms ▾...
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