Immune Thrombocytopenia (ITP)

Immune Thrombocytopenia (ITP)

TL;DR What is ITP? ▾ Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by a low platelet count. Platelets are essential blood cells that help form clots and prevent bleeding. Causes ▾ The immune system mistakenly attacks and destroys healthy...
Disseminated Intravascular Coagulation (DIC)

Disseminated Intravascular Coagulation (DIC)

TL;DR Definition ▾ Widespread activation of coagulation and fibrinolytic pathways as a secondary complication causing generalized hemorrhage and thrombosis. Causes ▾ Hypersensitivity reactions Incompatible transfusion reaction Incompatible organ transplantation...
Sickle Cell Anemia

Sickle Cell Anemia

TL;DR Definition ▾ Sickle cell anemia is a hereditary chronic hemolytic anemia caused by the production of Hb S (a qualitative hemoglobin defect due to a β-globin gene codon 6 mutation [glutamic acid → valine]) Pathophysiology ▾ Sickle cell anemia is a genetic...
Components of Donated Blood Products

Components of Donated Blood Products

TL;DR ExpiryStorageTransportExpiryIndicationsWhole bloodIn a blood bank refrigerator at 2℃ – 6℃Can be transported for the next 24h if maintained at 1℃ – 10℃ during transportation35 days in a closed system, 24 hr in an open systemAcute blood lossExchange...