Coagulation (Clotting) Disorders

Coagulation (Clotting) Disorders

Introduction Coagulation disorders are a group of conditions that disrupt the body’s normal blood clotting process. This disruption can manifest in two main ways: Increased Bleeding Tendency: This occurs when the blood has difficulty forming clots or the clots...
Platelet Function Disorders

Platelet Function Disorders

Introduction Platelet function disorders are a group of conditions that impair the ability of platelets to clump together (aggregate) and form blood clots. Platelets are blood cells that are essential for stopping bleeding by forming plugs at the site of injury. When...
Thrombocytopenia

Thrombocytopenia

Introduction  Thrombocytopenia is a condition characterized by an abnormally low level of platelets in the blood. In medical terms, a platelet count that falls below 150,000 platelets per microliter is generally considered thrombocytopenia. The physiological role...
Vascular Bleeding Disorders

Vascular Bleeding Disorders

Introduction Vascular bleeding disorders are a group of medical conditions marked by easy bruising  and spontaneous hemorrhage from capillaries and small blood vessels. Physiology of Normal Hemostasis The blood clotting cascade is a complex but crucial process...
Dengue & Thrombocytopenia

Dengue & Thrombocytopenia

Introduction Dengue infection is a mosquito-borne viral illness caused by the dengue virus. It’s a systemic infection, meaning it can affect multiple organ systems in the body. The severity of the infection can range from completely asymptomatic (no symptoms) to...