Introduction A systemic approach to anemia is a comprehensive strategy that tackles the condition from multiple angles, aiming for accurate diagnosis, effective treatment, and long-term management. It involves several steps that consider various factors to pinpoint...
Introduction Hereditary hemochromatosis is a genetic disorder that affects the body’s ability to regulate iron metabolism. This leads to excessive iron absorption from the diet, resulting in a buildup of iron in the body’s tissues and organs. Iron is a...
Introduction The discovery of the JAK2 V617F mutation revolutionized our understanding of myeloproliferative neoplasms (MPNs). This single nucleotide change, where a guanine (G) is replaced by a thymine (T) at position 1849 in exon 14 of the JAK2 gene, leads to...
Introduction Sideroblastic anemia is a type of anemia characterized by abnormal iron metabolism within red blood cell precursors. It belongs to a category called refractory anemia, which means the bone marrow has difficulty producing healthy red blood cells. The...
Introduction Macrocytic anemia is a specific type of anemia that combines two conditions: macrocytosis and anemia. Macrocytosis refers to a condition where red blood cells are larger than normal. It’s itself not a disease, but rather an abnormality detected in a...
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