Chronic Myeloid Leukemia (CML)

Chronic Myeloid Leukemia (CML)

TL;DR Chronic myeloid leukemia (CML) is a slower progressing clonal disorder of the hematopoietic stem cells where untreated patients progress to blast crisis stage after 3 – 5 years. It has a peak incidence at 40 – 60 years old. Signs and symptoms ▾...
Chronic Lymphocytic Leukemia (CLL)

Chronic Lymphocytic Leukemia (CLL)

TL;DR Chronic lymphocytic leukemia (CLL) is a slow progressing cancer due to overgrowth and accumulation of small incompetent mature-looking B-lymphocytes in the blood, bone marrow and lymphoid tissues. Small lymphocytic leukemia is a different clinical manifestation...
Acute Leukemia: An Overview

Acute Leukemia: An Overview

Introduction Acute leukemia, a devastating form of blood cancer, arises from the uncontrolled growth and proliferation of immature blood cells, known as blasts. These abnormal cells crowd out the healthy blood cells, disrupting the body’s ability to produce...
Perls’ Prussian Blue Staining

Perls’ Prussian Blue Staining

Procedure At A Glance Perls’ Prussian blue stain is used to histochemically detect and visualize ferric iron (Fe3+) deposits in cells and tissues. Preparation: Select and label positive control and test sample slides. Fix slides in absolute methanol for 10...