by MH Team | Oct 16, 2023 | Platelet Disorders
TL;DR Von Willebrand disease or disorder is an inherited coagulation disorder caused by mutations in the von Willebrand factor (vWF). vWF is a factor VIII carrier protein and mediates platelet adhesion to endothelium Pathogenesis ▾ Quantitative deficiency Type 1:...
by MH Team | Oct 15, 2023 | Transfusion Medicine
TL;DR Hemolytic disease of the newborn (HDN) also known as erythroblastosis fetalis is an allo-immune hemolytic anemia in the fetus or newborn. This is due to a fetal-maternal incompatibility for one of the red cell blood group systems i.e. Rh group causing maternal...
by MH Team | Oct 9, 2023 | Lab Protocols, White Blood Cells
Introduction Myeloperoxidase is a lysosomal enzyme, located in the azurophilic granules of the neutrophils and its precursors, eosinophils and monocytes. This MPO stain is mainly used to differentiate acute myeloid leukaemia from acute lymphoblastic leukaemia. MPO...
by MH Team | Oct 9, 2023 | Lab Protocols, White Blood Cells
Introduction Similar to the Leishman stain, May-Grünwald Giemsa (MGG) stain is part of the Romanowsky stains and adopts the same principle. May-Grünwald Giemsa (MGG) stain consists of May-Grünwald stain and Giemsa stain. MGG stain is used for morphology assessment of...
by MH Team | Oct 9, 2023 | White Blood Cells
TL;DR Hodgkin Lymphoma is a heterogeneous group of disorders caused by malignant lymphocytes that accumulate in lymph nodes presenting as lymphadenopathy. Hodgkin Lymphoma (HL) is differentiated from non-Hodgkin lymphoma by presence of Reed-Sternberg (RS) cells and a...
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