by MH Team | Nov 9, 2023 | Red Blood Cells
TL;DR Aplastic anemia (AA) causes pancytopenia (reduction of all blood cell types: RBCs, WBCs and platelets) due to aplasia (failure) of the bone marrow to function (to produce blood cells). Causes▾: Congenital e.g. Fanconi anemia, dyskeratosis congenita...
by MH Team | Nov 3, 2023 | Platelet Disorders
TL;DR Thrombotic thrombocytopenic purpura (TTP) is a type of thrombocytopenia due to deficiency of ADAMTS13 metalloprotease which leads to formation of platelet thrombi in microvessels. Signs and symptoms (pentad) ▾: Thrombocytopenia Microangiopathic...
by MH Team | Nov 3, 2023 | White Blood Cells
TL;DR T-cell ALL, or T-cell Acute Lymphoblastic Leukemia, is an aggressive hematologic malignancy resulting from the clonal expansion of immature T-cell precursors (lymphoblasts) that have failed to differentiate in the thymus. Epidemiology: Accounts for approximately...
by MH Team | Nov 2, 2023 | White Blood Cells
TL;DR B-cell ALL, or B-cell Acute Lymphoblastic Leukemia, is an aggressive malignancy of immature B-cell precursors or lymphoblasts in the bone marrow. Demographics: Most common childhood cancer; has a bimodal age distribution (peaks at <5 and >65 years)....
by MH Team | Nov 1, 2023 | Lab Protocols, White Blood Cells
Procedure At A Glance The Periodic Acid-Schiff stain (PAS staining) is a cost-effective method to primarily used to identify and characterize various hematological disorders, especially leukemias. Fix air-dried blood/bone marrow films for 1 minute at room temperature....
Recent Comments