by MH Team | Oct 19, 2023 | Red Blood Cells
TL;DR Definition ▾ Sickle cell anemia is a hereditary chronic hemolytic anemia caused by the production of Hb S (a qualitative hemoglobin defect due to a β-globin gene codon 6 mutation [glutamic acid → valine]) Pathophysiology ▾ Sickle cell anemia is a genetic...
by MH Team | Oct 18, 2023 | Transfusion Medicine
TL;DR ExpiryStorageTransportExpiryIndicationsWhole bloodIn a blood bank refrigerator at 2℃ – 6℃Can be transported for the next 24h if maintained at 1℃ – 10℃ during transportation35 days in a closed system, 24 hr in an open systemAcute blood lossExchange...
by MH Team | Oct 18, 2023 | Transfusion Medicine
TL;DR Definition ▾ Acute hemolytic transfusion reaction is an acute hemolysis due to the administration of antigenically incompatible red cells. Timing ▾ During transfusion or within 24 hours. Signs and Symptoms ▾ Fever: Often the first sign, occurring within minutes...
by MH Team | Oct 17, 2023 | White Blood Cells
TL;DR Multiple myeloma is a cancer of plasma cells, a type of white blood cell that produces antibodies. In this condition, abnormal plasma cells multiply uncontrollably and accumulate in the bone marrow. It is slightly more common in males than females and most...
by MH Team | Oct 17, 2023 | Platelet Disorders
TL;DR Hemophilia is an inherited coagulation disorder caused by mutations on factor VIII gene leading to deficiency in plasma factor VIII for hemophilia A while mutations on factor IX gene for hemophilia B causes decreased factor IX. It is an X-linked recessive...
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