by MH Team | Mar 14, 2025 | White Blood Cells
TL;DR AL amyloidosis is a systemic disease caused by a clonal plasma cell disorder, leading to the production and deposition of abnormal light-chain amyloid fibrils in organs and tissues. Pathophysiology ▾: Abnormal plasma cells overproduce light chains that...
by MH Team | Mar 12, 2025 | White Blood Cells
TL;DR Sjögren’s syndrome is a systemic autoimmune disease primarily targeting exocrine glands (dry eyes, mouth). Pathophysiology ▾: Lymphocytic infiltration, autoantibody production (anti-Ro/SSA, anti-La/SSB), genetic predisposition, and potential...
by MH Team | Mar 10, 2025 | White Blood Cells
TL;DR Waldenström macroglobulinemia (WM) is a rare, slow-growing B-cell lymphoma characterized by the overproduction of IgM monoclonal immunoglobulin by lymphoplasmacytic lymphoma (LPL) cells. Pathophysiology ▾: Primarily driven by the MYD88 L265P...
by MH Team | Mar 8, 2025 | Platelet Disorders
TL;DR Pulmonary embolism (PE) is a blockage in lung arteries, usually from a DVT. Risk factors involve Virchow’s triad ▾: hypercoagulability, venous stasis, endothelial injury. Pathophysiology ▾: Increased pulmonary resistance, right heart strain,...
by MH Team | Mar 5, 2025 | Tests
Have you ever felt inexplicably fatigued, experienced a sudden shortness of breath, or simply sensed that something wasn’t quite right? These subtle cues could be indicators of your blood oxygen saturation levels. Many people are unaware that their body’s...
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