by MyH Editorial Team | Oct 19, 2023 | Red Blood Cells
Key Takeaways Sickle cell disease (SCD) is a group of inherited blood disorders, not a single condition. All forms involve hemoglobin S (HbS), produced by a mutation in codon 6 of the β-globin gene that swaps glutamic acid for valine. Pathophysiology ▾:...
by MyH Editorial Team | Oct 18, 2023 | Transfusion Medicine
Key Takeaways Blood Products — Storage, Shelf Life & Indications Blood Product Storage & Shelf Life Indications Whole Blood Temp 1–6°C CPD 21 days CPDA-1 Up to 35 days Massive transfusion protocol Major obstetric hemorrhage Major blood loss...
by MyH Editorial Team | Oct 18, 2023 | Transfusion Medicine
Key Takeaways An acute hemolytic transfusion reaction (AHTR) is the rapid destruction of transfused red blood cells, occurring during or within 24 hours of a blood transfusion, and it is a medical emergency [1,3]. Timing ▾: During transfusion or within 24...
by MyH Editorial Team | Oct 17, 2023 | White Blood Cells
Key Takeaways Multiple myeloma is a cancer of plasma cells, a type of white blood cell that produces antibodies. In this condition, abnormal plasma cells multiply uncontrollably and accumulate in the bone marrow. It is slightly more common in males than females and...
by MyH Editorial Team | Oct 17, 2023 | Hemostasis Disorders
Key Takeaways Hemophilia is an inherited disorder of secondary hemostasis caused by a deficiency of factor VIII (hemophilia A) or factor IX (hemophilia B); both result in delayed, deep tissue bleeding rather than immediate surface bleeding. Clinical features ▾:...
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