Platelet Aggregation Test (PAT)

Platelet Aggregation Test (PAT)

Introduction When a blood vessel is injured, platelets rush to the scene, forming a sticky plug to seal the wound and prevent blood loss. This vital process is called platelet aggregation, and its effectiveness is often assessed through a crucial test: the platelet...
The Physiology of Hemostasis

The Physiology of Hemostasis

Introduction Hemostasis, a term derived from the Greek words for “blood” and “to stand,” is the remarkable biological process that keeps our blood flowing within the confines of our vascular network. It ensures that precious blood stays where...
Platelets: Guardians of Hemostasis

Platelets: Guardians of Hemostasis

Introduction Platelets are not just simple “band-aids” for blood vessels but provide the delicate balance between hemostasis and thrombosis. When a vessel wall is breached, platelets are the first responders. Drawn by the siren signal of exposed collagen,...
Myelodysplastic Syndromes (MDS): An Overview

Myelodysplastic Syndromes (MDS): An Overview

Introduction Myelodysplastic syndromes (MDS) encompass a diverse group of hematopoietic neoplasms caused by acquired mutations that disrupt the normal maturation of myeloid progenitors, leading to cytopenias in the peripheral blood. In MDS, hematopoiesis is...