Platelet Aggregation Test (PAT)

Platelet Aggregation Test (PAT)

Introduction When a blood vessel is injured, platelets rush to the scene, forming a sticky plug to seal the wound and prevent blood loss. This vital process is called platelet aggregation, and its effectiveness is often assessed through a crucial test: the platelet...
Physiology of Hemostasis

Physiology of Hemostasis

TL;DR Hemostasis, the intricate process of stopping and restarting blood flow after an injury, has different stages, each playing a crucial role and relying on the previous one for successful completion. Vascular Spasm ▾ Importance: The immediate constriction of...
Platelet

Platelet

Introduction Platelets are tiny cellular fragments that play a crucial role in the process of blood clotting, known as hemostasis. They are produced in the bone marrow from larger cells called megakaryocytes. When a vessel wall is breached, platelets are the first...
Myelodysplastic Syndromes (MDS): An Overview

Myelodysplastic Syndromes (MDS): An Overview

TL;DR Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic malignancies due to impaired maturation of myeloid progenitors leading to cytopenias and dysplasia of myeloid-lineage cells.  Peak incidence > 70 years old. Signs and symptoms ▾ Fatigue,...