TL;DR Definition ▾ G6PD deficiency anemia is an inherited hemolytic anemia due to red cell enzyme defect. X-linked recessive disorder – full expression only seen in males. G6PD deficiency symptoms & signs ▾ Usually asymptomatic Acute intravascular hemolytic...
TL;DR Definition ▾ Sickle cell anemia is a hereditary chronic hemolytic anemia caused by the production of Hb S (a qualitative hemoglobin defect due to a β-globin gene codon 6 mutation [glutamic acid → valine]) Pathophysiology ▾ Sickle cell anemia is a genetic...
TL;DR Beta-thalassemia is a hereditary hemoglobin disorder due to reduced or absence of beta-globin chain production leading to ineffective erythropoiesis and anemia. It is predominantly an autosomal recessive gene disorder. Epidemiology Approximately 1.5% of the...
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