Thrombophilia

Thrombophilia

TL;DR Thrombophilia is an abnormal predisposition to thrombosis (blood clotting) due to abnormalities in the coagulation system. Inherited Causes ▾: Factor V Leiden, Prothrombin gene mutation, deficiencies of Antithrombin, Protein C, or Protein S. Acquired Causes ▾:...
Catastrophic Antiphospholipid Syndrome

Catastrophic Antiphospholipid Syndrome

TL;DR Catastrophic Antiphospholipid Syndrome (CAPS) is a rare but life-threatening variant of Antiphospholipid Syndrome (APS). It’s thought to arise from a combination of existing APS (aPL), a precipitating event (like infection or surgery), and an amplifying...
Antiphospholipid Syndrome

Antiphospholipid Syndrome

TL;DR Antiphospholipid syndrome is an autoimmune disorder where the body’s immune system mistakenly attacks its own cells, specifically phospholipids, which are important for blood clotting. This can lead to blood clots and pregnancy problems.   Types ▾:...
Homocysteine Test

Homocysteine Test

Homocysteine is an amino acid naturally produced in the body. It’s broken down with the help of B vitamins. If your body doesn’t have enough of these vitamins, homocysteine levels can rise. Elevated homocysteine levels (hyperhomocysteinemia) are associated...
Homocysteine & Hyperhomocysteinemia

Homocysteine & Hyperhomocysteinemia

TL;DR Homocysteine is an amino acid, a building block of proteins, naturally produced in the body. It undergoes two main metabolic pathways: remethylation (requiring folate, vitamin B12, or betaine) and transsulfuration (requiring vitamin B6). Biomarker for...