by MH Team | Dec 18, 2023 | Platelet Disorders
TL;DR Hemostasis, the intricate process of stopping and restarting blood flow after an injury, has different stages, each playing a crucial role and relying on the previous one for successful completion. Vascular Spasm ▾ Importance: The immediate constriction of...
by MH Team | Dec 17, 2023 | Platelet Disorders
Introduction Platelets are tiny cellular fragments that play a crucial role in the process of blood clotting, known as hemostasis. They are produced in the bone marrow from larger cells called megakaryocytes. When a vessel wall is breached, platelets are the first...
by MH Team | Dec 14, 2023 | White Blood Cells
TL;DR Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic malignancies due to impaired maturation of myeloid progenitors leading to cytopenias and dysplasia of myeloid-lineage cells. Peak incidence > 70 years old. Signs and symptoms ▾ Fatigue,...
by MH Team | Dec 11, 2023 | Lab Protocols, Red Blood Cells
Introduction Hemolysate, a suspension of lysed red blood cells, plays a crucial role in both Hb electrophoresis and alkaline denaturation tests. These tests rely on the biochemical properties of hemoglobin to differentiate between different types of hemoglobin and...
by MH Team | Dec 11, 2023 | Lab Protocols, Platelet Disorders
Introduction The activated partial thromboplastin time (APTT) is a coagulation test that measures the intrinsic pathway of blood clotting. While the APTT itself is a valuable diagnostic tool, it can be further enhanced through the use of manual mixing studies. Mixing...
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