Introduction The direct antiglobulin test (DAT), also known as the Coombs test, is a crucial tool in diagnosing immune-mediated red blood cell (RBC) destruction (autoimmune hemolytic anemia). This test detects the presence of antibodies or complement proteins bound to...
TL;DR Primary hemostasis is the body’s rapid response to a broken blood vessel, plugging the leak before the “heavy artillery” of secondary hemostasis (coagulation cascade) kicks in. Key Players Platelets: They adhere to the injured vessel...
TL;DR Venous thromboembolism (VTE) is a condition where a blood clot (thrombosis) forms in a deep vein, usually in the leg (deep vein thrombosis) or pelvis, and can travel to the lungs, causing a pulmonary embolism. This is a serious condition that can be...
TL;DR Arterial thrombosis forms when a clot blocks an artery, cutting off blood supply to vital organs. Risk factors ▾: Age, smoking, high cholesterol, diabetes, and others. Symptoms ▾: Sudden pain, weakness, numbness, and discoloration can signal a clot. Related...
Introduction Apart from the ABO blood group system, the Rh blood group system is also important because anti-RhD can cause hemolytic transfusion reactions (highly immunogenic) and are normally IgG, thus able to cross the placenta and lead to hemolytic disease of the...
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