by MH Team | Nov 14, 2023 | Lab Protocols, Red Blood Cells
Introduction Beta thalassemia conventional PCR protocol is one of diagnostic laboratory methods used to identify the specific mutation involved in beta-thalassemia. Beta thalassemia is a group of inherited blood disorders characterized by a reduced or absent...
by MH Team | Nov 13, 2023 | Transfusion Medicine
TL;DR ABO blood group is the most important blood group system in transfusion and organ transplantation medicine. ABO antigens can be found on red cells, white cells, platelets and many circulating proteins. Transfusion incompatibility can cause acute...
by MH Team | Nov 9, 2023 | Lab Protocols, White Blood Cells
Introduction Leukocyte alkaline phosphatase (LAP) / Neutrophil alkaline phosphatase (NAP) stain stands as a valuable diagnostic tool, offering insights into the functionality of neutrophils, a critical component of the immune system. This enzymatic stain specifically...
by MH Team | Nov 9, 2023 | Red Blood Cells
TL;DR Aplastic anemia (AA) causes pancytopenia (reduction of all blood cell types: RBCs, WBCs and platelets) due to aplasia (failure) of the bone marrow to function (to produce blood cells). Causes of aplastic anemia (AA) ▾ Congenital e.g. Fanconi anemia,...
by MH Team | Nov 3, 2023 | Platelet Disorders
TL;DR Thrombotic thrombocytopenic purpura (TTP) is a type of thrombocytopenia due to deficiency of ADAMTS13 metalloprotease which leads to formation of platelet thrombi in microvessels. Signs and symptoms (pentad) ▾: Thrombocytopenia Microangiopathic hemolysis...
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