Essential Thrombocythemia (ET)

Essential Thrombocythemia (ET)

TL;DR Essential thrombocythemia (ET) is a chronic blood cancer characterized by an abnormal increase in platelet production by the bone marrow, leading to an increased risk of blood clots (thrombosis) and bleeding complications. Pathogenesis ▾ Primarily driven by...
Polycythemia Vera (PV)

Polycythemia Vera (PV)

TL;DR Polycythemia vera (PV) is a chronic blood disorder characterized by an increased production of red blood cells. It is caused by genetic mutations in the bone marrow particularly JAK2 mutations. Polycythemia Vera (PV) Symptoms ▾ May...
Myeloproliferative Neoplasms (MPN)

Myeloproliferative Neoplasms (MPN)

TL;DR Myeloproliferative neoplasms (MPNs) are a group of chronic blood cancers characterized by overproduction of one or more types of blood cells in the bone marrow. Classifications ▾ Essential Thrombocythemia (ET): Increased platelet count Polycythemia Vera (PV):...
Leukemia: An Overview

Leukemia: An Overview

TL;DR Leukemia is a cancer of the blood and bone marrow. It affects the cells responsible for fighting infection and carrying oxygen throughout the body. How does it occur? ▾ Normally, blood cells develop from stem cells in the bone marrow. In leukemia, the...
Lymphoma

Lymphoma

TL;DR Lymphoma is a group of cancers affecting the lymphatic system, vital for immunity. It encompasses both malignant (cancerous) and benign (non-cancerous) forms. Key differences ▾ Malignant lymphoma: Uncontrolled cell growth in lymphocytes, potentially spreading...