Peripheral Artery Disease (PAD)

Peripheral Artery Disease (PAD)

TL;DR Peripheral artery disease (PAD) is the narrowing of arteries outside the heart, primarily in the legs, due to atherosclerosis. Cause ▾: Atherosclerosis (plaque buildup) is the main cause. Symptoms ▾: Intermittent claudication (leg pain with exercise), rest pain,...
Heparin-Induced Thrombocytopenia

Heparin-Induced Thrombocytopenia

TL;DR Heparin-induced thrombocytopenia is an immune-mediated reaction to heparin that causes thrombocytopenia and an increased risk of thrombosis. Types ▾: Type I: Non-immune, transient, mild thrombocytopenia. Type II: Immune-mediated, potentially serious, associated...
Thrombophilia

Thrombophilia

TL;DR Thrombophilia is an abnormal predisposition to thrombosis (blood clotting) due to abnormalities in the coagulation system. Inherited Causes ▾: Factor V Leiden, Prothrombin gene mutation, deficiencies of Antithrombin, Protein C, or Protein S. Acquired Causes ▾:...