Abnormal White Blood Cell Morphology

Abnormal White Blood Cell Morphology

Introduction This article provides an overview of key findings in abnormal white blood cell morphology observed during a peripheral blood smear analysis. Understanding these abnormal white blood cell morphological changes can aid in diagnosing various underlying...
Red Blood Cell Inclusion Bodies

Red Blood Cell Inclusion Bodies

Introduction Red blood cell (RBC) morphology plays a crucial role in diagnosing hematological disorders. By examining the size, shape, and presence of RBC inclusion bodies, clinicians gain valuable insights into the underlying cause of abnormal blood function. RBC...
Abnormal Red Blood Cell (RBC) Morphology

Abnormal Red Blood Cell (RBC) Morphology

Introduction The unique red blood cell (RBC) morphology plays an important role in the optimal function of RBC as an oxygen transporter. This biconcave disc-shape offers a high surface area to volume ratio, allowing for efficient diffusion of oxygen molecules into and...
Leukocytosis

Leukocytosis

TL;DR Leukocytosis is an increase in white blood cell (WBC) count above the reference range. Significance ▾ Not a disease itself, but a marker of underlying infection, inflammation, or blood cancers. Causes ▾ Infections: Bacteria, viruses, fungi, or parasites battling...
Drug-Induced Immune Hemolytic Anemia (DIIHA)

Drug-Induced Immune Hemolytic Anemia (DIIHA)

TL;DR Drug-induced immune hemolytic anemia are caused by drugs that trigger an immune response to attack red blood cells (RBCs), leading to hemolytic anemia. Mechanism ▾ Hapten Model (most common) (Drug-dependent Antibody Model) Immune Complex Formation (less common)...