by MH Team | May 2, 2025 | Platelet Disorders
TL;DR Henoch-Schönlein Purpura (HSP) is a systemic small-vessel vasculitis characterized by palpable purpura, arthritis/arthralgia, abdominal pain, and often kidney involvement. Causes ▾: Exact cause unknown; likely triggered by infections (e.g., upper...
by MH Team | Apr 30, 2025 | Red Blood Cells
TL;DR Evans syndrome is. a rare autoimmune disorder with sequential or simultaneous autoimmune hemolytic anemia (AIHA) and immune thrombocytopenia (ITP), sometimes with autoimmune neutropenia (AIN). Pathophysiology ▾: Immune dysregulation leads to...
by MH Team | Apr 28, 2025 | Red Blood Cells
TL;DR Wilson’s disease is a rare genetic disorder causing toxic copper accumulation in the liver, brain, and other organs. Pathophysiology ▾: Defective ATP7B gene impairs copper excretion into bile and incorporation into ceruloplasmin, leading to copper...
by MH Team | Apr 26, 2025 | White Blood Cells
TL;DR Leukopenia is defined as a decrease in total white blood cells (leukocytes) below the normal range, increasing infection susceptibility. Normal Count: Typically 4,000-11,000 cells/µL; leukopenia is generally <4,000 cells/µL. Classification ▾:...
by MH Team | Apr 23, 2025 | Platelet Disorders
TL;DR Thrombocytosis or high platelet count is defined as elevated platelet count above the normal range (typically >450,000/μL). Reactive Thrombocytosis ▾: More common, caused by underlying conditions like infection, inflammation, iron deficiency,...
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