Platelet Function Disorders

Platelet Function Disorders

TL;DR Platelet function disorders disrupt the ability of platelets to clump together (aggregate) and form a proper clot. Platelets are blood cells essential for forming clots and stopping bleeding. Causes ▾ Inherited: Caused by genetic mutations affecting platelet...
Thrombocytopenia

Thrombocytopenia

TL;DR Thrombocytopenia is a condition characterized by an abnormally low platelets in the blood (generally below 150,000 platelets per microliter).  Causes ▾ Decreased Platelet Production: Bone marrow disorders, vitamin deficiencies, medications, infections. Increased...
Vascular Bleeding Disorders

Vascular Bleeding Disorders

TL;DR Vascular bleeding disorders encompass a diverse range of conditions marked by easy bruising and minor vessel bleeds. Inherited Vascular Disorders ▾ Hereditary hemorrhagic telangiectasia Connective tissue disorders e.g. Ehlers-Danlos syndromes and Pseudoxanthoma...
Dengue & Thrombocytopenia

Dengue & Thrombocytopenia

TL;DR Dengue Virus and Transmission ▾ Dengue is a viral infection spread by mosquitoes, particularly Aedes mosquitoes. There are four serotypes of the dengue virus, and infection with one serotype provides only temporary immunity to that specific type. Clinical...
Systemic Approach to Anemia

Systemic Approach to Anemia

TL;DR Detailed Clinical History ▾ Explore presenting illness (symptoms, onset, duration, severity). Investigate menstrual history (regularity, bleeding amount) for women. Review past medical, surgical, and drug history. Assess social history (occupation, travel,...