Burkitt Lymphoma

Burkitt Lymphoma

TL;DR Burkitt lymphoma (BL) is a highly aggressive (fast-growing) type of B-cell non-Hodgkin lymphoma. Pathogenesis ▾: c-myc translocation: A hallmark genetic abnormality involving the c-myc oncogene, leading to uncontrolled cell growth. Other genetic abnormalities...
Spleen

Spleen

TL;DR The spleen is a vital organ for immunity and blood filtration. Location ▾: Upper left quadrant of the abdomen, under the rib cage, near the stomach, left kidney, and diaphragm. Structure ▾: Capsule and trabeculae provide support.   White pulp (lymphatic tissue)...
Immunotherapy

Immunotherapy

TL;DR Immunotherapy is a type of cancer treatment that uses the body’s own immune system to fight cancer cells. It aims to boost the immune system’s ability to recognize and attack cancer cells. Mechanisms ▾ Checkpoint Inhibitors: Drugs that release the...
Erythropoietin

Erythropoietin

TL;DR Erythropoietin (EPO) is a vital hormone primarily produced by the kidneys. It plays a crucial role in stimulating the production of red blood cells in the bone marrow, a process known as erythropoiesis. Key Functions of EPO ▾ Stimulates Red Blood Cell...
Follicular Lymphoma

Follicular Lymphoma

TL;DR Follicular Lymphoma is a type of slow-growing, non-Hodgkin lymphoma affecting B-cells. Key Features Indolent Course: Often progresses slowly. Lymph Node Involvement: Commonly affects lymph nodes, especially in the neck, armpits, or groin. Histological Features:...