Natural Killer Cells

Natural Killer Cells

TL;DR Natural Killer (NK) cells are cytotoxic lymphocytes of the innate immune system, providing rapid responses against infected and cancerous cells without prior sensitization. Morphology ▾: They are large granular lymphocytes (LGLs) characterized by abundant...
Burkitt Lymphoma

Burkitt Lymphoma

TL;DR Burkitt lymphoma (BL) is a highly aggressive (fast-growing) type of B-cell non-Hodgkin lymphoma. Pathogenesis ▾: c-myc translocation: A hallmark genetic abnormality involving the c-myc oncogene, leading to uncontrolled cell growth. Other genetic abnormalities...
Immunotherapy

Immunotherapy

TL;DR Immunotherapy is a type of cancer treatment that uses the body’s own immune system to fight cancer cells. It aims to boost the immune system’s ability to recognize and attack cancer cells. Mechanisms ▾ Checkpoint Inhibitors: Drugs that release the...