by MH Team | Dec 20, 2023 | Lab Protocols, White Blood Cells
Introduction Immunohistochemistry (IHC) staining is a powerful technique that allows us to peek into the intricate world of protein expression within tissues. IHC staining transcends the limitations of traditional histological stains like hematoxylin and eosin...
by MH Team | Dec 19, 2023 | Lab Protocols, Platelet Disorders
Procedure-at-a-Glance Processing: Spin 1 (Slow): Centrifuge whole blood at ~200g for 10-15 mins to obtain Platelet Rich Plasma (PRP). Spin 2 (Fast): Centrifuge remaining blood at ~2000g for 15-20 mins to obtain Platelet Poor Plasma (PPP) (used as the...
by MH Team | Dec 18, 2023 | Platelet Disorders
TL;DR Hemostasis is the intricate process of stopping and restarting blood flow after an injury. It has different stages, each playing a crucial role and relying on the previous one for successful completion. Vascular Spasm ▾: The immediate constriction of...
by MH Team | Dec 17, 2023 | Platelet Disorders
TL;DR Platelet or a thrombocyte is a small, anucleated cellular fragment derived from bone marrow megakaryocyte. Lifespan & Count: They circulate for 7–10 days with a normal reference range of 150,000 – 450,000/µL. Morphology ▾: Resting:...
by MH Team | Dec 14, 2023 | White Blood Cells
TL;DR Myelodysplastic syndromes (MDS) are a group of clonal hematopoietic stem cell disorders characterized by ineffective hematopoiesis, resulting in peripheral blood cytopenias and a high risk of progression to Acute Myeloid Leukemia (AML). Peak incidence >...
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