by MH Team | Jan 11, 2024 | Platelet Disorders
TL;DR Key Function of Fibrinolysis: Dissolves fibrin clots after wound healing, restoring blood flow and preventing unwanted thrombus formation. Essential Players ▾ Plasminogen: The inactive precursor protein, waiting to be activated. Plasmin: The active enzyme...
by MH Team | Jan 8, 2024 | Platelet Disorders
TL;DR The coagulation cascade is a complex series of biochemical reactions that occur in the blood when a vessel is injured. It’s a tightly regulated process that involves numerous proteins, called coagulation factors, working together to form a blood clot and...
by MH Team | Jan 5, 2024 | Lab Protocols, Transfusion Medicine
Introduction The indirect antiglobulin test (IAT), also known as the indirect Coombs test, plays a crucial role in ensuring safe and compatible blood transfusions. This vital laboratory procedure delves into the world of antibodies, protecting against potentially...
by MH Team | Dec 31, 2023 | Lab Protocols, Transfusion Medicine
Introduction The direct antiglobulin test (DAT), also known as the Coombs test, is a crucial tool in diagnosing immune-mediated red blood cell (RBC) destruction (autoimmune hemolytic anemia). This test detects the presence of antibodies or complement proteins bound to...
by MH Team | Dec 30, 2023 | Platelet Disorders
TL;DR Primary hemostasis is the body’s rapid response to a broken blood vessel, plugging the leak before the “heavy artillery” of secondary hemostasis (coagulation cascade) kicks in. Key Players Platelets: They adhere to the injured vessel...
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