Neutropenia

Neutropenia

TL;DR Neutropenia is a quantitative deficiency of neutrophils, crucial for the innate immune system. Diagnosis relies on the absolute neutrophil count (ANC), classified by severity (mild, moderate, severe) and duration (acute, chronic). Causes ▾: Decreased bone...
Infectious Mononucleosis (Mono)

Infectious Mononucleosis (Mono)

TL;DR Infectious mononucleosis is an acute viral illness (primarily EBV) with classic triad: pharyngitis, fever, lymphadenopathy. Epidemiology ▾: Common in adolescents/young adults, spread globally, primarily via saliva. Causes ▾: Primarily Epstein-Barr...
Causes of Eosinophilia (High Eosinophils)

Causes of Eosinophilia (High Eosinophils)

TL;DR Eosinophilia (high eosinophils), defined as an elevated eosinophil count above 500 cells/µL, is a laboratory finding, not a disease itself, that signals a potential underlying medical issue requiring investigation based on its severity and the...
Chronic Myeloid Leukemia Treatment Strategies

Chronic Myeloid Leukemia Treatment Strategies

This blog post provides an overview of Chronic Myeloid Leukemia (CML) and its treatment strategies based on the most recent guideline (2025) from the National Comprehensive Cancer Network (NCCN). TL;DR Tyrosine kinase inhibitors (TKIs) are the primary treatment...
Hemoglobinuria: Overview and Causes

Hemoglobinuria: Overview and Causes

TL;DR Hemoglobinuria is the presence of free hemoglobin in urine, distinct from hematuria (whole RBCs). It occurs when intravascular hemolysis overwhelms the body’s hemoglobin-handling capacity (haptoglobin, hemopexin). Causes ▾: Transfusion reactions,...
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