Introduction The sickle cell test, also known as the dithionite solubility test, is a simple and rapid method used to detect the presence of sickle cell disease or sickle cell trait. Sickle cell disease (SCD) is a group of inherited blood disorders characterized by...
TL;DR Key Function of Fibrinolysis: Dissolves fibrin clots after wound healing, restoring blood flow and preventing unwanted thrombus formation. Essential Players ▾ Plasminogen: The inactive precursor protein, waiting to be activated. Plasmin: The active enzyme...
TL;DR The coagulation cascade is a complex series of biochemical reactions that occur in the blood when a vessel is injured. It’s a tightly regulated process that involves numerous proteins, called coagulation factors, working together to form a blood clot and...
Introduction The indirect antiglobulin test (IAT), also known as the indirect Coombs test, plays a crucial role in ensuring safe and compatible blood transfusions. This vital laboratory procedure delves into the world of antibodies, protecting against potentially...
Introduction The direct antiglobulin test (DAT), also known as the Coombs test, is a crucial tool in diagnosing immune-mediated red blood cell (RBC) destruction (autoimmune hemolytic anemia). This test detects the presence of antibodies or complement proteins bound to...
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